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Osteoarthritis

Pathophysiology

Calcium crystal deposition diseases: Beyond gout

In this review, the main clinical manifestations of calcium pyrophosphate dihydrate and basic calcium phosphate crystal deposition are discussed, along with the biological effects of these crystals, current therapeutic approaches and future directions in therapy [read more].
McCarthy GM, Dunne A. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0078-5

06-09-2018 | Calcium crystal deposition disease | Review | Article

Calcium crystal deposition diseases: Beyond gout

McCarthy GM, Dunne A. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0078-5

04-07-2018 | Osteoarthritis | Article

Early morphologic changes in trapeziometacarpal joint bones with osteoarthritis

Schneider MTY et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.06.008

13-06-2018 | Osteoarthritis | Review | Article

Molecular transport in articular cartilage: What have we learned from the past 50 years?

DiDomenico CD, Lintz M, Bonassar LJ. Nat Rev Rheumatol 2018; 14: 393–403. doi: 10.1038/s41584-018-0033-5

08-06-2018 | Osteoarthritis | Article

The role of thigh muscle and adipose tissue in knee osteoarthritis progression in women: Data from the Osteoarthritis Initiative

Kemnitz J et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.05.020

08-06-2018 | Pain | Review | Article

Cannabinoids for the treatment of rheumatic diseases: Where do we stand?

Katz-Talmor D et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0025-5

04-06-2018 | Inflammation | Review | Article

Novel insights into the role of inflammasomes in autoimmune and metabolic rheumatic diseases

Deuteraiou K et al. Rheumatol Int 2018. doi: 10.1007/s00296-018-4074-5

15-05-2018 | Osteoarthritis | Review | Article

Defining the osteoarthritis patient: Back to the future

Dobson GP et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.04.018

11-05-2018 | Osteoarthritis | Review | Article

The role of radiography and MRI for eligibility assessment in DMOAD trials of knee OA

Roemer FW et al. Nat Rev Rheumatol 2018; 14: 372–380. doi: 10.1038/s41584-018-0010-z

05-04-2018 | Osteoarthritis | Article

CCL17 blockade as a therapy for osteoarthritis pain and disease

Lee MC et al. Arthritis Res Ther 2018; 20: 62. doi: 10.1186/s13075-018-1560-9

09-03-2018 | Rheumatoid arthritis | Article

Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis

Kohno Y et al. BMC Musculoskelet Disord 2018; 19: 78. doi: 10.1186/s12891-018-1998-6

08-03-2018 | Osteoarthritis | Review | Article

Calcium-containing crystals and osteoarthritis: An unhealthy alliance

Conway R, McCarthy GM. Curr Rheumatol Rep 2018; 20: 13. doi: 10.1007/s11926-018-0721-9

07-03-2018 | Osteoarthritis | Article

Detection of differentially expressed genes involved in osteoarthritis pathology

Tian H. J Orthop Surg Res 2018; 13: 49. doi: 10.1186/s13018-018-0734-0

26-02-2018 | Osteoarthritis | Review | Article

Peripheral mechanisms contributing to osteoarthritis pain

Syx D et al. Curr Rheumatol Rep 2018; 20: 9. doi: 10.1007/s11926-018-0716-6

08-02-2018 | Pathophysiology | Review | Article

Proteinases and their receptors in inflammatory arthritis: An overview

Nat Rev Rheumatol 2018; 14: 170–180. doi: 10.1038/nrrheum.2018.17

Authors:
Katerina Oikonomopoulou, Eleftherios P. Diamandis, Morley D. Hollenberg, Vinod Chandran

05-02-2018 | Osteoarthritis | Article

Serum and synovial fluid cytokine profiling in hip osteoarthritis: Distinct from knee osteoarthritis and correlated with pain

Ren G et al. BMC Musculoskelet Disord 2018; 19: 39. doi: 10.1186/s12891-018-1955-4

30-01-2018 | Pathophysiology | Review | Article

mTOR signaling in skeletal development and disease

Chen J, Long F. Bone Res 2018; 6: 1. doi: 10.1038/s41413-017-0004-5

24-01-2018 | Pathogenesis | Review | Article

Moving towards a molecular taxonomy of autoimmune rheumatic diseases

Barturen G et al. Nat Rev Rheumatol 2018; 14: 75–93. doi: 10.1038/nrrheum.2017.220

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