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Osteoarthritis

Pathophysiology

06-09-2018 | Calcium crystal deposition disease | Review | Article

Calcium crystal deposition diseases: Beyond gout

McCarthy GM, Dunne A. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0078-5

04-07-2018 | Osteoarthritis | Article

Early morphologic changes in trapeziometacarpal joint bones with osteoarthritis

Schneider MTY et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.06.008

20-06-2018 | Osteoarthritis | Article

Connective tissue growth factor contributes to joint homeostasis and osteoarthritis severity by controlling the matrix sequestration and activation of latent TGFβ

Tang X et al. Ann Rheum Dis 2018. doi: 10.1136/annrheumdis-2018-212964

13-06-2018 | Osteoarthritis | Review | Article

Molecular transport in articular cartilage: What have we learned from the past 50 years?

DiDomenico CD, Lintz M, Bonassar LJ. Nat Rev Rheumatol 2018; 14: 393–403. doi: 10.1038/s41584-018-0033-5

08-06-2018 | Pain | Review | Article

Cannabinoids for the treatment of rheumatic diseases: Where do we stand?

Katz-Talmor D et al. Nat Rev Rheumatol 2018. doi: 10.1038/s41584-018-0025-5

08-06-2018 | Osteoarthritis | Article

The role of thigh muscle and adipose tissue in knee osteoarthritis progression in women: Data from the Osteoarthritis Initiative

Kemnitz J et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.05.020

04-06-2018 | Inflammation | Review | Article

Novel insights into the role of inflammasomes in autoimmune and metabolic rheumatic diseases

Deuteraiou K et al. Rheumatol Int 2018. doi: 10.1007/s00296-018-4074-5

23-05-2018 | Osteoarthritis | Article

Associations between molecular biomarkers and MR-based cartilage composition and knee joint morphology: Data from the Osteoarthritis Initiative

Joseph GB et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.04.019

15-05-2018 | Osteoarthritis | Review | Article

Defining the osteoarthritis patient: Back to the future

Dobson GP et al. Osteoarthritis Cartilage 2018. doi: 10.1016/j.joca.2018.04.018

11-05-2018 | Osteoarthritis | Review | Article

The role of radiography and MRI for eligibility assessment in DMOAD trials of knee OA

Roemer FW et al. Nat Rev Rheumatol 2018; 14: 372–380. doi: 10.1038/s41584-018-0010-z

05-04-2018 | Osteoarthritis | Article

CCL17 blockade as a therapy for osteoarthritis pain and disease

Lee MC et al. Arthritis Res Ther 2018; 20: 62. doi: 10.1186/s13075-018-1560-9

09-03-2018 | Rheumatoid arthritis | Article

Comparison of mesenchymal stem cells obtained by suspended culture of synovium from patients with rheumatoid arthritis and osteoarthritis

Kohno Y et al. BMC Musculoskelet Disord 2018; 19: 78. doi: 10.1186/s12891-018-1998-6

08-03-2018 | Osteoarthritis | Review | Article

Calcium-containing crystals and osteoarthritis: An unhealthy alliance

Conway R, McCarthy GM. Curr Rheumatol Rep 2018; 20: 13. doi: 10.1007/s11926-018-0721-9

07-03-2018 | Osteoarthritis | Article

Detection of differentially expressed genes involved in osteoarthritis pathology

Tian H. J Orthop Surg Res 2018; 13: 49. doi: 10.1186/s13018-018-0734-0

26-02-2018 | Osteoarthritis | Review | Article

Peripheral mechanisms contributing to osteoarthritis pain

Syx D et al. Curr Rheumatol Rep 2018; 20: 9. doi: 10.1007/s11926-018-0716-6

08-02-2018 | Pathophysiology | Review | Article

Proteinases and their receptors in inflammatory arthritis: An overview

Nat Rev Rheumatol 2018; 14: 170–180. doi: 10.1038/nrrheum.2018.17

05-02-2018 | Osteoarthritis | Article

Serum and synovial fluid cytokine profiling in hip osteoarthritis: Distinct from knee osteoarthritis and correlated with pain

Ren G et al. BMC Musculoskelet Disord 2018; 19: 39. doi: 10.1186/s12891-018-1955-4

24-01-2018 | Pathogenesis | Review | Article

Moving towards a molecular taxonomy of autoimmune rheumatic diseases

Barturen G et al. Nat Rev Rheumatol 2018; 14: 75–93. doi: 10.1038/nrrheum.2017.220

29-04-2017 | Osteoarthritis | Review | Article

The epigenomic landscape in osteoarthritis

This review introduces basic concepts in epigenetics and their recent applications to the study of osteoarthritis development and progression.

Simon TC, Jeffries MA. Curr Rheumatol Rep 2017;19:30. doi:10.1007/s11926-017-0661-9

Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB

15-05-2017 | Osteoarthritis | Review | Article

Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB

The authors review studies focusing on two multi-functional signaling pathways, discussing the roles of these signaling pathways in osteoarthritis pathophysiology and articular cartilage homeostasis.

Saito T, Tanaka S. Arthritis Res Ther 2017;19:94. doi:10.1186/s13075-017-1296-y